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產(chǎn)品規(guī)格
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BN41382R-100ul
100ul
￥2360.00
交叉反應：Mouse,Rat(predicted:Human,Horse) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
BN41382R-200ul
200ul
￥3490.00
交叉反應：Mouse,Rat(predicted:Human,Horse) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
產(chǎn)品描述
| 英文名稱 | PGGT1B |
| 中文名稱 | 香葉烯基轉移酶1β抗體 |
| 別 名 | PGGT1B; GGTase-I beta; GGTase-1 beta; BGGI; Geranylgeranyl transferase type I subunit beta; Geranylgeranyl transferase type-1 subunit beta; GGTase-I-beta; GGTI; PGGT1B; PGTB1_HUMAN; Type I protein geranyl-geranyltransferase subunit beta; |
| 研究領域 | 細胞生物 免疫學 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Mouse, Rat, (predicted: Human, Horse, ) |
| 產(chǎn)品應用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 42kDa |
| 細胞定位 | 細胞核 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PGGT1 beta:301-377/377 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010] Function: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Acts on the Rac1, Rac2, Rap1A and Rap1B proteins. The beta subunit is responsible for peptide-binding. Subunit: Heterodimer of an alpha and a beta subunit. Similarity: Belongs to the protein prenyltransferase subunit beta family. Contains 4 PFTB repeats. SWISS: P53609 Gene ID: 5229 Database links: Entrez Gene: 5229 Human Entrez Gene: 225467 Mouse Omim: 602031 Human SwissProt: P53609 Human SwissProt: Q8BUY9 Mouse Unigene: 254006 Human Unigene: 262096 Mouse Unigene: 393044 Mouse Unigene: 10031 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
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