ww.783成人A片,亚洲精品乱码久久久久久蜜桃91,www.71.com色婬免费,91午夜理伦私人影院
最近搜索:細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
首頁>>免疫學(xué)>>一抗>>膽汁酸受體抗體
膽汁酸受體抗體
  • 產(chǎn)品貨號:
    BN42192R
  • 中文名稱:
    膽汁酸受體抗體
  • 英文名稱:
    Rabbit anti-NR1H4 Polyclonal antibody
  • 品牌:
    Biorigin
  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN42192R-50ul

    50ul

    ¥1486.00

    交叉反應(yīng):Mouse,Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat) 推薦應(yīng)用:WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN42192R-100ul

    100ul

    ¥2360.00

    交叉反應(yīng):Mouse,Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat) 推薦應(yīng)用:WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN42192R-200ul

    200ul

    ¥3490.00

    交叉反應(yīng):Mouse,Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat) 推薦應(yīng)用:WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱NR1H4
中文名稱膽汁酸受體抗體
別    名Bile Acid Receptor NR1H4; BAR; FXR; Farnesoid X activated receptor; Farnesoid X receptor; Farnesoid X-activated receptor; Farnesol receptor HRR 1; Farnesol receptor HRR-1; Farnesol receptor HRR1; FXR; HRR 1; HRR1;NR1H4_HUMAN; Nuclear receptor subfamily 1 group H member 4; Retinoid X receptor interacting protein 14; Retinoid X receptor-interacting protein 14; RIP 14; RIP14; RXR interacting protein 14; RXR-interacting protein 14.




研究領(lǐng)域腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  新陳代謝  表觀遺傳學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=3ug/test ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量56kDa
細(xì)胞定位細(xì)胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human FXR/Bile Acid Receptor NR1H4:175-280/486 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and binds DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, and several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed “orphan receptors” because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.

Function:
Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.

Subunit:
eterodimer of NR1H4 and RXR. After activation by agonist binding, interacts with a coactivator, NCOA1 or NCOA2 (By similarity). Interacts with CARM1 and SMARD1.

Subcellular Location:
Nucleus.

Post-translational modifications:
Methylation may increase transactivation of target genes.

Similarity:
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.

SWISS:
Q96RI1

Gene ID:
9971

Database links:

Entrez Gene: 9971 Human

Entrez Gene: 20186 Mouse

Entrez Gene: 60351 Rat

Omim: 603826 Human

SwissProt: Q96RI1 Human

SwissProt: Q3V1T8 Mouse

SwissProt: Q60641 Mouse

SwissProt: Q5XI75 Rat

SwissProt: Q62735 Rat

Unigene: 282735 Human

Unigene: 3095 Mouse

Unigene: 42943 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.















image.png

image.png

image.png

image.png

image.png

image.png

国产乱码精品一品二品 | 综合区亚一洲线观看免费 | 老司机午夜福利私人玩物 | 久久久秘一区二区三区 | 国产传媒啊啊啊视频 | 日日鲁鲁夜夜爽爽爽狠狠 | 亚洲精品黄站视频 | 空姐一级毛片免费看 | 大乳爆乳午夜A∨片91 | 爱爱动态大图120秒 在线无码精品秘 人口 | 国产欧美欧美在线香蕉在线 | 1000部国产精品成人观看 | 四季AV一区二区三区 | 久久久久久免费免费麻辣 | 嫖妓老熟女嗷嗷叫91在线 | 成人小视频免费观看 | 精品人妻少妇一级毛片免费 | 日日夜夜爱爱鲁鲁舔舔 | 女教师一级特黄大片630 | 寡妇偷人A片一二三区 | 四川少妇BBw搡BBBB槡BBBB 91精品国自产在线观看 | 亚洲综合熟女久久久30p蜜臀 | 农村少妇野外A片WWw | 国产校花久色在线观看 | 在线观看av女大学生黑料 | 最新中文字幕在线观看 | 人人添人人澡久久婷亚洲AV | 亚洲一区二区无码乱伦 | 欧美中文字幕在线观看 | 好大好爽一区二区蜜桃 | 欧美一级黃色A片免费看蜜桃 | 性做爰A片欧美激情艳妇20p | 四川少妇BBw搡BBBB槡BBBB 四川少妇bbw搡bbbb搡bbbb | 欧美丝袜AAAAA片 | 国产91在线 | 北美洲 | 蜜桃传媒第1页-葡萄Av | 91麻豆产精品久久久久久夏晴子 | 人妻久久久精品996系列A片 | 偷拍国语对白露脸在线 | 无码国产精品一区二区免费式冫忍 | 国产一级二级三级电影 |